RESUMO
Sarcoidosis is a rare multisystem chronic inflammatory disease in children. We present a case of a five-year-old child with clinical features mimicking several diseases, including tuberculosis. After failure of treatment based on the suspected diagnosis, an axillary lymph node biopsy showed noncaseating granulomas compatible with sarcoidosis and appropriate treatment was then started.
Assuntos
Sarcoidose/diagnóstico , Anti-Helmínticos/uso terapêutico , Anti-Inflamatórios/uso terapêutico , Biópsia , Brasil , Pré-Escolar , Diagnóstico Diferencial , Feminino , Humanos , Linfoma/diagnóstico , Prednisolona/uso terapêutico , Sarcoidose/tratamento farmacológico , Tiabendazol/uso terapêutico , Tomografia Computadorizada por Raios X , Tuberculose/diagnósticoRESUMO
Abstract Sarcoidosis is a rare multisystem chronic inflammatory disease in children. We present a case of a five-year-old child with clinical features mimicking several diseases, including tuberculosis. After failure of treatment based on the suspected diagnosis, an axillary lymph node biopsy showed noncaseating granulomas compatible with sarcoidosis and appropriate treatment was then started.
Assuntos
Humanos , Feminino , Pré-Escolar , Sarcoidose/diagnóstico , Sarcoidose/tratamento farmacológico , Tiabendazol/uso terapêutico , Tuberculose/diagnóstico , Biópsia , Brasil , Prednisolona/uso terapêutico , Tomografia Computadorizada por Raios X , Diagnóstico Diferencial , Linfoma/diagnóstico , Anti-Helmínticos/uso terapêutico , Anti-Inflamatórios/uso terapêuticoRESUMO
Visceral leishmaniasis is a systemic disease that is potentially severe and endemic in Brazil. It clinically manifests as fever, weight loss, swelling, hepatosplenomegaly, paleness, and edema. In this study, we discuss a case of a 1-year-old child diagnosed with refractory visceral leishmaniasis after being treated with liposomal amphotericin B in two distinct occasions. Considering the persistent clinical features and weak response to conventional treatment, a combination therapy with liposomal amphotericin B (ambisome), n-methylglucamine antimoniate (glucantime), and pentamidine isethionate was initiated, and response to treatment was good.
Assuntos
Anfotericina B/administração & dosagem , Antiprotozoários/administração & dosagem , Leishmaniose Visceral/tratamento farmacológico , Meglumina/administração & dosagem , Compostos Organometálicos/administração & dosagem , Pentamidina/administração & dosagem , Quimioterapia Combinada , Humanos , Lactente , Masculino , Antimoniato de MegluminaRESUMO
Abstract Visceral leishmaniasis is a systemic disease that is potentially severe and endemic in Brazil. It clinically manifests as fever, weight loss, swelling, hepatosplenomegaly, paleness, and edema. In this study, we discuss a case of a 1-year-old child diagnosed with refractory visceral leishmaniasis after being treated with liposomal amphotericin B in two distinct occasions. Considering the persistent clinical features and weak response to conventional treatment, a combination therapy with liposomal amphotericin B (ambisome), n-methylglucamine antimoniate (glucantime), and pentamidine isethionate was initiated, and response to treatment was good.
